PROBLEM
- Karyotyping is the process by which photographs of chromosomes are taken in order to determine the chromosome complement of an individual, including the number of chromosomes and any abnormalities. The term is also used for the complete set of chromosomes in a species or in an individual organism and for a test that detects this complement or measures the number.
- Condensed chromosomes classification can result in low accuracy and sensitivity and only expert cytogeneticists can perform karyotype.
- Cytogeneticists normally perform all the analysis steps including: (Isolating metaphase and non- metaphase objects, chromosomes labeling according to length and centromere position, translating the chromosomes to the desired positions in the final karyogram. Revising the resulting karyogram according to the banding pattern.
SOLUTION
- Our AKS can perform all the karyotype steps which includes chromosomes segmentation, classification, and ordering automatically, using different metaphase images.
- With our AKS, any cytogeneticist can perform automated karyotype system and can segment and classify condensed chromosomes with high accuracy and sensitivity. It can perform all the metaphase chromosomes analysis automatically and robustly and in a fraction of the time.
